MATERIAL SAFETY DATA SHEET - Malathion 96%

MSDS (MALATHION TECH.) 

MATERIAL SAFETY DATA SHEET

SECTION 1 - IDENTIFICATION OF THE SUBSTANCE AND COMPANY

Company Address: The National Company For Agrochemicals & Investment

473 El_horreya St., Bolkly Alexandria-Egypt

Tel.: (203) 5440640/1 Fax.: (203) 5411150

Product Name: Malathion Tech.

CAS RN: 121-75-5

CUS (Customs union and statistics number): 19456

CN-Code (Combined Nomenclature code): 2930 90 70

Chemical Name: Diethyl (dimethoxythiophosphorylthio) succinate

Chemical family: Organophosphorus

SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS

Component Percentage

Malathion 96%

SECTION 3 - IDENTIFICATION OF HAZARDS

Emergency Overview:

- Cholinesterase inhibitor.

- Harmful if swallowed.

- Harmful if absorbed through skin or inhaled.

- Causes slight eye irritation.

- Avoid breathing product vapors or spray mist.

- Avoid contact with eyes, skin or clothing.

- Keep out of reach of children.

Symptoms of over exposure are headaches, nausea, vomiting, cramps, weakness, blurred

vision, pin point pupils, tightness in chest, labored breathing, nervousness, sweating, watering

of eyes, drooling, muscle spasms and coma.

Potential Health Hazards:

EYE CONTACT: May cause eye injury.

SKIN CONTACT: Irritation may occur. The most likely rout of entry.

INGESTION: Contact a physician if material is ingested.

INHALATION: Contact a physician if material is inhaled and breathing is difficult.

Signs and symptoms of short-term (acute) exposure:

INHALATION: Malathion is a cholinesterase inhibitor of low mammalian toxicity. However

storage at too high temperatures may induce formation of the much more toxic and synergistic

contaminant isomalathion. Malathion and isomalathion can affect you when breathed in and

can cause organophosphorous poisoning. Symptoms of poisoning may include headache,

nausea, vomiting, blurred vision, tightness in chest, drooling, frothing of mouth and nose,

convulsions, coma and death.

SKIN CONTACT: Direct skin contact may causes irritation. Malathion and isomalathion can

be rapidly absorbed through all skin surfaces. Causes symptoms similar to those listed for

inhalation.

EYE CONTACT: Direct eye contact causes irritation. Malathion and isomalathion can be

rapidly absorbed through all skin and eye surfaces. Causes symptoms similar to those listed for

inhalation.

INGESTION: Malathion and isomalathion are poisons through ingestion. Causes symptoms

similar to those listed for inhalation.

Effects of long-term (chronic) exposure: Prolonged or repeated overexposure may cause

behavioural changes. Carcinogcnicity: See TOX1COLOGICAL INFORMATION.

SECTION 4- FIRST AID MEASURES

INHALATION: Immediately remove victim to fresh air. If breathing has stopped, begin

artificial respiration immediately. Transport to a clinic or hospital immediately.

SKIN: Immediately flush skin with running water for at least 15 minutes, while removing

contaminated clothing and shoes. Obtain medical attention immediately. Thoroughly clean

contaminated clothing before re-use.

EYES: Immediately flush eyes with running water for at least 15 minutes. Get medical attention

immediately.

INGESTION: If ingested, have victims drunk 6 to 8 ounces of water. Induce vomiting

immediately only under the direct supervision of qualified medical personnel. Never give

anything by mouth if victim is unconscious or convulsing. Transport to a clinic or hospital

immediately.

NOTE TO PHYSICIAN: Malathion is a cholinesterase inhibitor affecting the central and

peripheral nervous systems and producing respiratory and cardiac depression. Decontamination

procedures such as whole body washing, gastric lavage and administration of activated charcoal

are often required. If symptoms are present, administer atropine sulphate in large doses. Two to

four mg intravenously or intramuscularly as soon as possible. Repeat at 5 to 10 minute’s

intervals until signs of atropinization appear and maintain full atropinization until all

organophosphorous is metabolised. Obidoxime chloride (Toxogonin), alternatively pralidoxime

chloride (2-PAM), is a pharmacological antidote and may be administered as an adjunct to, but

not a substitute for atropine, which is a symptomatic and often life-saving antidote. At first sign

of pulmonary edema, the patient should be given supplemental oxygen and treated

symptomatically. Continued absorption of Malathion may occur and relapse may occiu" after

initial improvement. VERY CLOSE SUPERVISION OF THE PATIENT IS INDICATED FOR

AT LEAST 48 HOURS.

SECTION 5 - FIRE FIGHTING MEASURES

FLASHPOINT: 163 oC (Pensky-Martens closed cup)

FLAMMABLE LIMITS: lower -1, upper -7

FIRE AND EXPLOSION HAZARD: Alert medical personnel to be ready to treat for

pesticide poisoning, should treatment be necessary

EXTINGUISHING MEDIA: Dry chemical or carbon dioxide for small fires. Water spray or

foam for large fires.

Special fire fighting procedure: wear self-contained breathing apparatus and full fire fighting

clothing. Use as little water as possible. Dike area to prevent pesticide runoff. Use spray or fog.

Conduct fire fighting upwind.

MSDS (MALATHION TECH.) 

SECTION 6 - ACCIDENTAL RELEASE MEASURES

PERSONAL PRECAUTIONS: Restrict access to area until completion of clean up. Ensure

clean-trained personnel conduct up only. All persons dealing with clean up should wear the

appropriate chemically protective equipment. Refer to Section 8, EXPOSURE CONTROLS

AND PERSONAL PROTECTION, for additional information on acceptable personal

protective equipment.

ENVIRONMENTAL PRECAUTIONS: Ensure spilled product does not enter drains, sewers,

waterways, or confined spaces.

Dike far ahead of the spill for later recovery or disposal. Washings must be prevented from

entering surface water drains. Uncontrolled discharge into watercourses must be alerted to the

appropriate regulatory body.

SPILL RESPONSE/CLEANUP: Eliminate all sources of heat, sparks and flame. Ventilate

area of release. Stop leak if you can do so without risk. Notify the appropriate authorities. For

spills on the floor or other impervious surfaces, absorb spill with inert, non-combustible

absorbent material, such as hydrated lime. Fuller's earth or other absorbent clays. Scoop up and

place contaminated absorbent material into suitable containers for later disposal. Rinse spills

area with soda lye. Do not flush to sewer or allow entering confined spaces. Large spills that

soak into the ground should be dug up, placed in suitable containers and disposed of

appropriately. Notify the appropriate authorities.

PROHIBITED MATERIALS: None known.

SECTION 7 - HANDLING AND STORAGE

HANDLING: keep out of reach of children. Very dangerous. Poisonous if absorbed by skin

contact, inhaled or swallowed. Avoid contact with eyes and skin. Do not touch or rub eyes, nose

or mouth with hand when handling granules. Wear protective clothing and equipment as above.

Keep away from volatile chemicals and sources of ignition.

If product on skin, immediately wash area with soap and water. After use and before eating,

drinking or smoking washes hands, arms and face thoroughly with soap and water. After each

day’s use, wash gloves respirator and contaminated clothing with detergent and warm water. 

STORAGE: KEEP OUT OF REACH OF CHILDREN: Store in the closed, original

container in a dry, cool, well-ventilated area. Do not store for prolonged periods in direct

sunlight. Store in a locked room or place away from children, animals, food, feedstuffs, seed

and fertilisers. DO NOT store in or around the home. Store below 45°C. Avoid extreme heat.

Keep dry – moisture can increase handling hazards.

Flammability Non-flammable. However, dust / air mixtures can build up static electrical

charges and fine dust may form explosive mixtures in air.

SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION

VENTILATION AND ENGINEERING CONTROLS: If handled indoors, provide

mechanical exhaust ventilation to keep concentrations below specified TLV's and pel's.

RESPIRATORY PROTECTION: Respiratory protection is required. Wear a pesticide

respirator jointly approved by the MSHA and NIOSH. Advice should be sought from respiratory

protection specialists.

PROTECTIVE GLOVES: Wear impervious chemical gloves, such as barrier laminate, butyl

rubber, nitrile rubber or viton. Advice should be sought from glove suppliers on the proper

selection of gloves.

EYE PROTECTION: Wear safety glasses with side shields or chemical splash goggles to

prevent splashes from entering the eyes.

OTHER PROTECTIVE EQUIPMENT: Wear appropriate protective clothing to prevent skin

contact, such as coveralls or long sleeved shirt, long pants, and shoes and socks. Other protective

equipment, such as an eyewash station and safety shower, may be required depending on

exposure and on workplace standards.

GENERAL HYGIENE CONSIDERATIONS: Do not breathe vapors or mists. Avoid contact

all contact with eyes, skin and clothing. Before removing gloves, wash them with soap and

water. Always wash hands, face and arms with soap and water before smoking, eating or

drinking. After work, take off all protective equipment, work clothes and shoes, and wash with

soap and water. Respirator should be cleaned and filter replaced according to manufacturer's

instructions.

Wear only clean, uncontaminated clothes when leaving place of work. Persons working with

this product for a longer period should have frequent blood tests for cholinesterase levels. If the

cholinesterase levels fall below a critical point, no further exposure should be allowed until it

has been determined, by means of blood tests that cholinesterase levels have returned to

normal.

MSDS (MALATHION TECH.) 

SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL DESCRIPTION: Clear, amber liquid.

ODOR: A mild mercaptan-like odor (skunk) of moderate intensity.

MOLECULAR WEIGHT: 330.3

MOLECULAR FORMULA: C10H19O6PS2

BOILING POINT: 156-157oC/0.7 mmHg.

MELTING POINT: 2.85oC

SPECIFIC GRAVITY: 1.23 (oC)

VAPOR PRESSURE: 5.3 mPa (30 oC)

SOLUBILITY: In water 145 mg/l (25oC).

SECTION 10 - STABILITY AND REACTIVITY

CHEMICAL STABILITY: Relatively stable in neutral aqueous media. Decomposed by strong

acid and alkali; hydrolysis DT50 107 d (pH 5), 0.5 d (pH 9) (all 25 oC)

CONDITIONS TO AVOID: Extreme heat and sparks. Avoid contact with iron, strong alkali

and storage above 120 oF.

INCOMPATIBILITY WITH OTHER MATERIALS: Incompatible with alkaline materials

and strong oxidizers.

HAZARDOUS POLYMERIZATION: Will not occur under normal temperature and pressure.

SECTION 11 - TOXICOLOGICAL INFORMATION

Oral: LD50 for Rats (M): 1375-5500 mg/kg.

LD50 for mice: 775-3320 mg/kg.

Dermal: LD50 for Rats: > 2000 mg/kg

LD50 for Rabbits: 4100-8800 mg/kg.

Inhalation: LC50 (4h) for Rats > 5.2 mg/l air.

Eye Irritation: Slight eye irritant (rabbits).

Skin Irritation: Mild irritant to skin (rabbits).

NOEL: In (2y) on rats, the only effect seen at 500 ppm (29 mg/kg b.w daily) was inhibition of

cholinesterase in plasma and red blood cells.

Target Organs: Central Nervous System.

Carcinogenicity: Not classified in humans

ADI: 0.3 mg/kg b.w

MSDS (MALATHION TECH.) 

SECTION 12 - ECOLOGICAL INFORMATION

CHEMICAL FATE INFORMATION: The active ingredient, Malathion, is readily

biodegradable. It undergoes rapid degradation in the environment and, without problems, in

sewage treatment plants. No adverse effects are observed at concentrations up to 100 mg/L in

wastewater treatment plants. Degradation occurs aerobically and anaerobically, and biologically

as well as biologically. Under normal conditions, Malathion is of medium mobility in soil, but is

degraded rapidly. The product should not be allowed to enter drains or watercourses or be

deposited where it can affect ground or surface waters. Do not discharge product unmonitored

into the environment.

ECOTOXICOLOGICAL INFORMATION: The bioconcentration factor (BCF) of Malathion

is 96 (average for several fish species). Malathion is toxic to birds, fish, aquatic invertebrates,

and aquatic life stages of amphibians and highly toxic to bees. The acute toxicity to wildlife

species is:

Fish: 96-Hr LC50, Rainbow trout (Salrno gairdneri) = 110 ppb, LC50, Bluegill sunfish = 120 ppb

Invertebrates: 48-HrEC50, Daphnids (Daphnia magna) = 1.0 μg/L.

Birds: LD50, Bobwhite quail (Colinus virginicinus) = 400 mg/kg.

LD50 mallard ducks 1485 ppm

Bees: 24-HrLD50, worker honeybees, acute oral = 0.38 μg/bee.

24-Hr LD50, worker honey-bees, topical = 0.27 μg/bee

SECTION 13 - DISPOSAL CONSIDERATIONS

WASTE: Pesticide wastes are toxic and hazardous. Dispose of in accordance with applicable

and local laws and regulations. Do not discharge or pour into soil, drainage system or bodies of

water.

CONTAINER: Triple rinse (or equivalent). Then offer for recycling or reconditioning, or

puncture and dispose of in a sanitary landfill, or incineration, or if allowed by state and local

authorities, by burning (plastic containers). If burned, stay out of smoke.

MSDS (MALATHION TECH.) 

SECTION 14 - TRANSPORT INFORMATION

PROPER SHIPPING NAME: Environmentally Hazardous Substance, Liquid, N.O.S.

UN NUMBER: UN 3082

DOT HAZARD CLASS: 9

DOT PACKING GROUP: PG III

DOT PRIMARY/SUBSIDIARY LABEL: Keep Away From Food

DOT PRIMARY/SUBSIDIARY PLACARD: Keep Away From Food

SECTION 15 - REGULATORY INFORMATION

Risk Symbols

Xn: Harmful,

Risk Phrases

R22: Harmful if swallowed

SECTION 16 - OTHER INFORMATION

DISCLAIMER: The information presented herein is based on available data from reliable

sources and is correct to the best of Agrochem knowledge. Agrochem makes no warranty,

express or implied, regarding the accuracy of the data or the results obtained from the use of

this product. Nothing herein may be construed as recommending any practice or any product in

violation of any law or regulations. The user is solely responsible for determining the

suitability of any material or product for a specific purpose and for adopting any appropriate

safety precautions. We disclaim all liability for injury or damage stemming from any improper

use of the material or product described herein.

Info : Agrochem.com/MSDS/insecticide-technical/malathion