Monday, January 7, 2013

MATERIAL SAFETY DATA SHEET - Malathion 96%


MSDS (MALATHION TECH.) 

MATERIAL SAFETY DATA SHEET
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE AND COMPANY

Company Address: The National Company For Agrochemicals & Investment
473 El_horreya St., Bolkly Alexandria-Egypt
Tel.: (203) 5440640/1 Fax.: (203) 5411150
Product Name: Malathion Tech.
CAS RN: 121-75-5
CUS (Customs union and statistics number): 19456
CN-Code (Combined Nomenclature code): 2930 90 70
Chemical Name: Diethyl (dimethoxythiophosphorylthio) succinate
Chemical family: Organophosphorus

SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Component Percentage
Malathion 96%

SECTION 3 - IDENTIFICATION OF HAZARDS
Emergency Overview:
- Cholinesterase inhibitor.
- Harmful if swallowed.
- Harmful if absorbed through skin or inhaled.
- Causes slight eye irritation.
- Avoid breathing product vapors or spray mist.
- Avoid contact with eyes, skin or clothing.
- Keep out of reach of children.
Symptoms of over exposure are headaches, nausea, vomiting, cramps, weakness, blurred
vision, pin point pupils, tightness in chest, labored breathing, nervousness, sweating, watering
of eyes, drooling, muscle spasms and coma.

Potential Health Hazards:
EYE CONTACT: May cause eye injury.
SKIN CONTACT: Irritation may occur. The most likely rout of entry.
INGESTION: Contact a physician if material is ingested.
INHALATION: Contact a physician if material is inhaled and breathing is difficult.
Signs and symptoms of short-term (acute) exposure:
INHALATION: Malathion is a cholinesterase inhibitor of low mammalian toxicity. However
storage at too high temperatures may induce formation of the much more toxic and synergistic
contaminant isomalathion. Malathion and isomalathion can affect you when breathed in and
can cause organophosphorous poisoning. Symptoms of poisoning may include headache,
nausea, vomiting, blurred vision, tightness in chest, drooling, frothing of mouth and nose,
convulsions, coma and death.
SKIN CONTACT: Direct skin contact may causes irritation. Malathion and isomalathion can
be rapidly absorbed through all skin surfaces. Causes symptoms similar to those listed for
inhalation.
EYE CONTACT: Direct eye contact causes irritation. Malathion and isomalathion can be
rapidly absorbed through all skin and eye surfaces. Causes symptoms similar to those listed for
inhalation.
INGESTION: Malathion and isomalathion are poisons through ingestion. Causes symptoms
similar to those listed for inhalation.
Effects of long-term (chronic) exposure: Prolonged or repeated overexposure may cause
behavioural changes. Carcinogcnicity: See TOX1COLOGICAL INFORMATION.

SECTION 4- FIRST AID MEASURES
INHALATION: Immediately remove victim to fresh air. If breathing has stopped, begin
artificial respiration immediately. Transport to a clinic or hospital immediately.
SKIN: Immediately flush skin with running water for at least 15 minutes, while removing
contaminated clothing and shoes. Obtain medical attention immediately. Thoroughly clean
contaminated clothing before re-use.
EYES: Immediately flush eyes with running water for at least 15 minutes. Get medical attention
immediately.

INGESTION: If ingested, have victims drunk 6 to 8 ounces of water. Induce vomiting
immediately only under the direct supervision of qualified medical personnel. Never give
anything by mouth if victim is unconscious or convulsing. Transport to a clinic or hospital
immediately.
NOTE TO PHYSICIAN: Malathion is a cholinesterase inhibitor affecting the central and
peripheral nervous systems and producing respiratory and cardiac depression. Decontamination
procedures such as whole body washing, gastric lavage and administration of activated charcoal
are often required. If symptoms are present, administer atropine sulphate in large doses. Two to
four mg intravenously or intramuscularly as soon as possible. Repeat at 5 to 10 minute’s
intervals until signs of atropinization appear and maintain full atropinization until all
organophosphorous is metabolised. Obidoxime chloride (Toxogonin), alternatively pralidoxime
chloride (2-PAM), is a pharmacological antidote and may be administered as an adjunct to, but
not a substitute for atropine, which is a symptomatic and often life-saving antidote. At first sign
of pulmonary edema, the patient should be given supplemental oxygen and treated
symptomatically. Continued absorption of Malathion may occur and relapse may occiu" after
initial improvement. VERY CLOSE SUPERVISION OF THE PATIENT IS INDICATED FOR
AT LEAST 48 HOURS.

SECTION 5 - FIRE FIGHTING MEASURES
FLASHPOINT: 163 oC (Pensky-Martens closed cup)
FLAMMABLE LIMITS: lower -1, upper -7
FIRE AND EXPLOSION HAZARD: Alert medical personnel to be ready to treat for
pesticide poisoning, should treatment be necessary
EXTINGUISHING MEDIA: Dry chemical or carbon dioxide for small fires. Water spray or
foam for large fires.
Special fire fighting procedure: wear self-contained breathing apparatus and full fire fighting
clothing. Use as little water as possible. Dike area to prevent pesticide runoff. Use spray or fog.
Conduct fire fighting upwind.

MSDS (MALATHION TECH.) 
SECTION 6 - ACCIDENTAL RELEASE MEASURES
PERSONAL PRECAUTIONS: Restrict access to area until completion of clean up. Ensure
clean-trained personnel conduct up only. All persons dealing with clean up should wear the
appropriate chemically protective equipment. Refer to Section 8, EXPOSURE CONTROLS
AND PERSONAL PROTECTION, for additional information on acceptable personal
protective equipment.
ENVIRONMENTAL PRECAUTIONS: Ensure spilled product does not enter drains, sewers,
waterways, or confined spaces.
Dike far ahead of the spill for later recovery or disposal. Washings must be prevented from
entering surface water drains. Uncontrolled discharge into watercourses must be alerted to the
appropriate regulatory body.
SPILL RESPONSE/CLEANUP: Eliminate all sources of heat, sparks and flame. Ventilate
area of release. Stop leak if you can do so without risk. Notify the appropriate authorities. For
spills on the floor or other impervious surfaces, absorb spill with inert, non-combustible
absorbent material, such as hydrated lime. Fuller's earth or other absorbent clays. Scoop up and
place contaminated absorbent material into suitable containers for later disposal. Rinse spills
area with soda lye. Do not flush to sewer or allow entering confined spaces. Large spills that
soak into the ground should be dug up, placed in suitable containers and disposed of
appropriately. Notify the appropriate authorities.
PROHIBITED MATERIALS: None known.

SECTION 7 - HANDLING AND STORAGE
HANDLING: keep out of reach of children. Very dangerous. Poisonous if absorbed by skin
contact, inhaled or swallowed. Avoid contact with eyes and skin. Do not touch or rub eyes, nose
or mouth with hand when handling granules. Wear protective clothing and equipment as above.
Keep away from volatile chemicals and sources of ignition.
If product on skin, immediately wash area with soap and water. After use and before eating,
drinking or smoking washes hands, arms and face thoroughly with soap and water. After each
day’s use, wash gloves respirator and contaminated clothing with detergent and warm water. 
STORAGE: KEEP OUT OF REACH OF CHILDREN: Store in the closed, original
container in a dry, cool, well-ventilated area. Do not store for prolonged periods in direct
sunlight. Store in a locked room or place away from children, animals, food, feedstuffs, seed
and fertilisers. DO NOT store in or around the home. Store below 45°C. Avoid extreme heat.
Keep dry – moisture can increase handling hazards.
Flammability Non-flammable. However, dust / air mixtures can build up static electrical
charges and fine dust may form explosive mixtures in air.

SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
VENTILATION AND ENGINEERING CONTROLS: If handled indoors, provide
mechanical exhaust ventilation to keep concentrations below specified TLV's and pel's.
RESPIRATORY PROTECTION: Respiratory protection is required. Wear a pesticide
respirator jointly approved by the MSHA and NIOSH. Advice should be sought from respiratory
protection specialists.
PROTECTIVE GLOVES: Wear impervious chemical gloves, such as barrier laminate, butyl
rubber, nitrile rubber or viton. Advice should be sought from glove suppliers on the proper
selection of gloves.
EYE PROTECTION: Wear safety glasses with side shields or chemical splash goggles to
prevent splashes from entering the eyes.
OTHER PROTECTIVE EQUIPMENT: Wear appropriate protective clothing to prevent skin
contact, such as coveralls or long sleeved shirt, long pants, and shoes and socks. Other protective
equipment, such as an eyewash station and safety shower, may be required depending on
exposure and on workplace standards.
GENERAL HYGIENE CONSIDERATIONS: Do not breathe vapors or mists. Avoid contact
all contact with eyes, skin and clothing. Before removing gloves, wash them with soap and
water. Always wash hands, face and arms with soap and water before smoking, eating or
drinking. After work, take off all protective equipment, work clothes and shoes, and wash with
soap and water. Respirator should be cleaned and filter replaced according to manufacturer's
instructions.
Wear only clean, uncontaminated clothes when leaving place of work. Persons working with
this product for a longer period should have frequent blood tests for cholinesterase levels. If the
cholinesterase levels fall below a critical point, no further exposure should be allowed until it
has been determined, by means of blood tests that cholinesterase levels have returned to
normal.

MSDS (MALATHION TECH.) 
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL DESCRIPTION: Clear, amber liquid.
ODOR: A mild mercaptan-like odor (skunk) of moderate intensity.
MOLECULAR WEIGHT: 330.3
MOLECULAR FORMULA: C10H19O6PS2
BOILING POINT: 156-157oC/0.7 mmHg.
MELTING POINT: 2.85oC
SPECIFIC GRAVITY: 1.23 (oC)
VAPOR PRESSURE: 5.3 mPa (30 oC)
SOLUBILITY: In water 145 mg/l (25oC).

SECTION 10 - STABILITY AND REACTIVITY
CHEMICAL STABILITY: Relatively stable in neutral aqueous media. Decomposed by strong
acid and alkali; hydrolysis DT50 107 d (pH 5), 0.5 d (pH 9) (all 25 oC)
CONDITIONS TO AVOID: Extreme heat and sparks. Avoid contact with iron, strong alkali
and storage above 120 oF.
INCOMPATIBILITY WITH OTHER MATERIALS: Incompatible with alkaline materials
and strong oxidizers.
HAZARDOUS POLYMERIZATION: Will not occur under normal temperature and pressure.

SECTION 11 - TOXICOLOGICAL INFORMATION
Oral: LD50 for Rats (M): 1375-5500 mg/kg.
LD50 for mice: 775-3320 mg/kg.
Dermal: LD50 for Rats: > 2000 mg/kg
LD50 for Rabbits: 4100-8800 mg/kg.
Inhalation: LC50 (4h) for Rats > 5.2 mg/l air.
Eye Irritation: Slight eye irritant (rabbits).
Skin Irritation: Mild irritant to skin (rabbits).
NOEL: In (2y) on rats, the only effect seen at 500 ppm (29 mg/kg b.w daily) was inhibition of
cholinesterase in plasma and red blood cells.
Target Organs: Central Nervous System.
Carcinogenicity: Not classified in humans
ADI: 0.3 mg/kg b.w

MSDS (MALATHION TECH.) 
SECTION 12 - ECOLOGICAL INFORMATION
CHEMICAL FATE INFORMATION: The active ingredient, Malathion, is readily
biodegradable. It undergoes rapid degradation in the environment and, without problems, in
sewage treatment plants. No adverse effects are observed at concentrations up to 100 mg/L in
wastewater treatment plants. Degradation occurs aerobically and anaerobically, and biologically
as well as biologically. Under normal conditions, Malathion is of medium mobility in soil, but is
degraded rapidly. The product should not be allowed to enter drains or watercourses or be
deposited where it can affect ground or surface waters. Do not discharge product unmonitored
into the environment.
ECOTOXICOLOGICAL INFORMATION: The bioconcentration factor (BCF) of Malathion
is 96 (average for several fish species). Malathion is toxic to birds, fish, aquatic invertebrates,
and aquatic life stages of amphibians and highly toxic to bees. The acute toxicity to wildlife
species is:
Fish: 96-Hr LC50, Rainbow trout (Salrno gairdneri) = 110 ppb, LC50, Bluegill sunfish = 120 ppb
Invertebrates: 48-HrEC50, Daphnids (Daphnia magna) = 1.0 μg/L.
Birds: LD50, Bobwhite quail (Colinus virginicinus) = 400 mg/kg.
LD50 mallard ducks 1485 ppm
Bees: 24-HrLD50, worker honeybees, acute oral = 0.38 μg/bee.
24-Hr LD50, worker honey-bees, topical = 0.27 μg/bee

SECTION 13 - DISPOSAL CONSIDERATIONS
WASTE: Pesticide wastes are toxic and hazardous. Dispose of in accordance with applicable
and local laws and regulations. Do not discharge or pour into soil, drainage system or bodies of
water.
CONTAINER: Triple rinse (or equivalent). Then offer for recycling or reconditioning, or
puncture and dispose of in a sanitary landfill, or incineration, or if allowed by state and local
authorities, by burning (plastic containers). If burned, stay out of smoke.

MSDS (MALATHION TECH.) 
SECTION 14 - TRANSPORT INFORMATION
PROPER SHIPPING NAME: Environmentally Hazardous Substance, Liquid, N.O.S.
UN NUMBER: UN 3082
DOT HAZARD CLASS: 9
DOT PACKING GROUP: PG III
DOT PRIMARY/SUBSIDIARY LABEL: Keep Away From Food
DOT PRIMARY/SUBSIDIARY PLACARD: Keep Away From Food

SECTION 15 - REGULATORY INFORMATION
Risk Symbols
Xn: Harmful,
Risk Phrases
R22: Harmful if swallowed

SECTION 16 - OTHER INFORMATION
DISCLAIMER: The information presented herein is based on available data from reliable
sources and is correct to the best of Agrochem knowledge. Agrochem makes no warranty,
express or implied, regarding the accuracy of the data or the results obtained from the use of
this product. Nothing herein may be construed as recommending any practice or any product in
violation of any law or regulations. The user is solely responsible for determining the
suitability of any material or product for a specific purpose and for adopting any appropriate
safety precautions. We disclaim all liability for injury or damage stemming from any improper
use of the material or product described herein.

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